Overview of global API and intermediates industry development

API and intermediates industry is in the middle of the pharmaceutical industry chain. With the expansion of the pharmaceutical industry as a whole, the scale of the global API and intermediates market is also increasing year by year, especially in recent years, the number of original drugs whose patents have expired is increasing, and the number of generic drugs is rising rapidly. Between 2019 and 2024, about $198 billion in sales of original drug patents are expected to expire. Accordingly, the market demand for APIs and intermediates is also greatly improved, and the global API and intermediates industry is expected to maintain a stable growth and a good development trend.

At present, the main API production regions in the world are China, India, Japan, North America and Western Europe, among which China and India become the main API production and export countries.

Chemical API and intermediates industry has the characteristics of long synthesis route, complex synthesis technology and high technology control requirements. At present, Europe and the United States and other pharmaceutical raw material preparation power mainly on the basis of their own grasp of more advanced chemical synthesis process and patent and technical advantages to earn high value-added products, while China is more on the basis of raw materials and labor costs in bulk varieties of production. 

Although the production technology level of most of China's API and intermediate raw materials, especially bulk products, is close to the world's leading level and has strong competitiveness in the global market, there is still a big gap between China and foreign advanced levels in the field of high value-added products such as high-end characteristic raw materials and patented API. It is urgent for Chinese enterprises to improve their own technological level through strengthening research and development, and enter the market of high-end featured raw materials and patent API with higher profit level.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Special Fine chemicals, synthesis of novel and known molecular compounds, have substantial experience in process development, scale up and commercialization.

Dimethylthiocarbamoyl chloride is an organosulfur compound with the formula (CH3)2NC(S)Cl. A yellow solid, it is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.