Analysis of intermediates market and of Dimethylthiocarbamoyl chloride

Pharmaceutical production needs a large number of special chemicals, most of these chemicals were originally produced by the pharmaceutical industry, but with the deepening of social division of labor and the progress of production technology, the pharmaceutical industry will transfer some pharmaceutical intermediates to chemical enterprises. Pharmaceutical intermediates are fine chemical products, the production of pharmaceutical intermediates has become a major industry in the international chemical industry.

Advanced intermediates, in fact, is more expensive pharmaceutical intermediates. This pharmaceutical intermediate is processed from the original material/raw material through several steps and has a high added value. The word may be used to distinguish it from the base ingredient. China needs more than 2000 kinds of pharmaceutical intermediates every year, and the demand is more than 2.5 million tons.

In the production of pharmaceutical intermediates, there are multiple production modes of CMO, CDMO and CRO. In recent years, the difficulty of developing new drugs worldwide has increased, the cost has increased, the return on investment has decreased, and as patents have expired, a large number of generic drugs have been launched, which has driven the drug development to lower-cost regions. By 2021, the CMO/CDMO market in China will exceed 100 billion US dollars. With the transfer of global pharmaceutical CMO industry to China, the production and demand of pharmaceutical intermediates in China will increase, and the development potential of Chinese pharmaceutical intermediates market is huge.

In terms of market competition, China's pharmaceutical intermediates have excellent quality and relatively low price, so their popularity in the global market is increasing and their market share is expanding. In the future, China's pharmaceutical intermediates have greater development potential in the market.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Special Fine chemicals, synthesis of novel and known molecular compounds, have substantial experience in process development, scale up and commercialization. 

Dimethylthiocarbamoyl chloride is an organosulfur compound with the formula (CH3)2NC(S)Cl. A yellow solid, it is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement. Dimethylthiocarbamoyl chloride was used in chemoselective deoxygenation of pyridine-N-oxides. It was used in the synthesis of (±)-thia-calanolide A. It was used as starting reagent in the synthesis of dimethylthiocarbamates.